Methylamine → HCID 178484396, compound

HRID 1277467Notes

Reaction equation

HRID 1277467 reaction equation
[Br:1][C:2]1[NH:6][CH:5]=[N:4][C:3]=1[CH2:7][CH2:8][CH2:9][CH2:10][NH2:11].[N+](C=C(SC)SC)([O-])=O.[N+:21]([CH:24]=[C:25](SC)[NH:26][CH2:27]CCCC1N=CNC=1Br)([O-:23])=[O:22].CN>>[N+:21]([CH:24]=[C:25]([NH:26][CH3:27])[NH:11][CH2:10][CH2:9][CH2:8][CH2:7][C:3]1[N:4]=[CH:5][NH:6][C:2]=1[Br:1])([O-:23])=[O:22]

Participants

5

Reactant 4

HCID 6329MethylamineHCID 836231,1-Bis(methylthio)-2-nitroethyleneHCID 178503822HCID 178503822, compoundHCID 178510963HCID 178510963, compound

Product 1

HCID 178484396HCID 178484396, compound

Procedure

When 5-bromo-4-(4-aminobutyl)imidazole is reacted with 1-nitro-2,2-bis-methylthioethylene according to the procedure of Example 8(i) and the resultant 1-nitro-2-methylthio-2-[4-(5-bromo-4-imidazolyl)butylamino]ethylene, m.p. 157°-158° treated with methylamine by the procedure of Example 8(ii), the title compound, m.p. 145°-148° is produced.

Sources & evidence

ORD record
ord-18b3e60a3a994241b30c26f05875d5e0
Source dataset
uspto-grants-1981_07
Patent number
US04277485

Reaction notes

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