HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 2-Amino-N-(1,1-dimethylpentyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 2-Methylhexan-2-ol | HCID 12240 | — |
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | N-(Cyanomethyl)-phthalimide | HCID 345881 | — |
| Reactant | N-(1,1-dimethylpentyl)-2-phthalimidoacetamide | HCID 23454152 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Benzene | HCID 241 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-N-(1,1-dimethylpentyl)acetamide | HCID 23454138 | — |
Reaction Steps
2-Phthalimidoacetonitrile (14.4 g.) was reacted with 2-methylhexan-2-ol (7.5 g.) in glacial acetic acid by the addition of concentrated sulphuric acid (15 ml.) according to the process described in Example 1. The resulting N-(1,1-dimethylpentyl)-2-phthalimidoacetamide was recrystallisedfrom benzene, m.p. 189°-190° C. It was then reacted with hydrazine hydrate (2.8 g.) in ethanol (100 ml.) as in Example 2 and the product purified as its hydrogen oxalate; 2-amino-N-(1,1-dimethylpentyl)acetamide hydrogen oxalate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04277498 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-6bc557d5f4ec495ebea9e7d1de9450a3 |
| Source note | uspto-grants-1981_07 |