反应详情

2-Phthalimidoacetonitrile (14.4 g.) was reacted with 2-methylhexan-2-ol (7.5 g.) in glacial acetic acid by the addition of concentrated sulphuric acid (15 ml.) according to the process described in Example 1. The resulting N-(1,1-dimethylpentyl)-2-phthalimidoacetamide was recrystallisedfrom benzene, m.p. 189°-190° C. It was then reacted with hydrazine hydrate (2.8 g.) in ethanol (100 ml.) as in Example 2 and the product purified as its hydrogen oxalate; 2-amino-N-(1,1-dimethylpentyl)acetamide hydrogen oxalate.

1. customthe product purified as its hydrogen oxalate