反应详情

温度

10 °C

36 G. of 7-formyl-3-methyl-octa-2,4,6-trien-1-oic acid ethyl ester are dissolved in 600 ml. of absolute ethanol. The solution is treated portionwise with 1.8 g. of sodium borohydride. The mixture is stirred for 2 hours at 10° C. then poured onto ice water and 3 N aqueous hydrochloric acid and extracted with ether. The ether extract is washed successively with water, a saturated aqueous sodium bicarbonate solution and once more with water, dried over sodium sulfate and evaporated. There is obtained 8-hydroxy-3,7-dimethyl-octa-2,4,6-trien-1-oic acid ethyl ester.

1. additionThe solution is treated portionwise with 1.8 g
2. extractionextracted with ether
3. extractionThe ether extract
4. washis washed successively with water
5. dry with materiala saturated aqueous sodium bicarbonate solution and once more with water, dried over sodium sulfate
6. customevaporated