Potassium Carbonate → HCID 23452870, compound

HRID 1277587Notes

Reaction equation

HRID 1277587 reaction equation
[CH3:1][O:2][C:3](=[O:18])[C:4]1[CH:13]=[C:12]([OH:14])[CH:11]=[C:6]([C:7]([O:9][CH3:10])=[O:8])[C:5]=1[N+:15]([O-:17])=[O:16].C(=O)([O-])[O-].[K+].[K+].[C:25]([O:29][C:30](=[O:33])[CH2:31]Br)([CH3:28])([CH3:27])[CH3:26]>CC(C)=O>[C:25]([O:29][C:30](=[O:33])[CH2:31][O:14][C:12]1[CH:11]=[C:6]([C:7]([O:9][CH3:10])=[O:8])[C:5]([N+:15]([O-:17])=[O:16])=[C:4]([C:3]([O:2][CH3:1])=[O:18])[CH:13]=1)([CH3:28])([CH3:27])[CH3:26]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 79177tert-Butyl bromoacetateHCID 23452882HCID 23452882, compound

Product 1

HCID 23452870HCID 23452870, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of 2.55 g. of dimethyl-5-hydroxy-2-nitroisophthalate (prepared as in Example 15, Part B) in 25 ml. of acetone is added 0.69 g. of anhydrous potassium carbonate, followed by 1.95 g. of tert-butylbromoacetate. The mixture is stirred and refluxed for 20 hr. After this time, the cooled reaction mixture is poured with rapid stirring into 200 ml. of ice-cold 1% hydrochloric acid. The solid is collected and washed well with water. Yield 3.4 g.; m.p. 106°-108° C.

Workup

  1. temperaturerefluxed for 20 hr
  2. customAfter this time, the cooled reaction mixture
  3. additionis poured
  4. stirringwith rapid stirring into 200 ml
  5. customThe solid is collected
  6. washwashed well with water

Sources & evidence

ORD record
ord-ec4069ba697f46c0be11723c2de61a46
Source dataset
uspto-grants-1981_07
Patent number
US04278598

Reaction notes

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