Potassium Hydroxide → HCID 12882322, compound

Participants

Reaction Steps

Into 15 ml of ethanol, 430 mg of potassium hydroxide was dissolved and 1.7 g (0.00512 mole) of ethyl α-(p-cyclohexylphenoxy)α-cyclohexylacetate was added. The mixture was heated on a water bath at 65° to 70° C. for 90 minutes and then ethanol was distilled off under a reduced pressure and the residue was admixed with water and washed twice with benzene. The water layer was acidified with 10% HCl aq.sol. to precipitate a precipitate. The precipitate was filtrated and washed with water and dried. The product was recrystallized from n-hexane to obtain 0.7 g of α-(p-cyclohexylphenoxy)α-cyclohexylacetic acid (yield: 44.9%).

Provenance & Evidence