Methylamine → HCID 23453201, compound

HRID 1277656Notes

Reaction equation

HRID 1277656 reaction equation
[Cl:1][C:2]1[N:3]([CH2:8][C:9]([O:11]C)=O)[C:4]([Cl:7])=[CH:5][CH:6]=1.[CH3:13][NH2:14]>>[Cl:1][C:2]1[N:3]([CH2:8][C:9]([NH:14][CH3:13])=[O:11])[C:4]([Cl:7])=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 23453203HCID 23453203, compound

Product 1

HCID 23453201HCID 23453201, compound

Procedure

A mixture of methyl (2,5-dichloro-1H-pyrrol-1-yl)acetate (1.04 g) and methylamine (5 cm3, 33% solution in ethanol) was allowed to stand at room temperature overnight. The solvent was then evaporated and the residue crystallised from isopropanol to give the title compound (0.65 g) m.p. 193°-4° C.

Workup

  1. customThe solvent was then evaporated
  2. customthe residue crystallised from isopropanol

Sources & evidence

ORD record
ord-a866f8b2178245d599befeee8ff36438
Source dataset
uspto-grants-1981_07
Patent number
US04278685

Reaction notes

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