HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 23453199, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | HCID 14351973 | HCID 14351973 | — |
| Product | HCID 23453199 | HCID 23453199 | — |
Reaction Steps
Ethyl 2-(1H-pyrrol-1-yl)propionate (Ger. Offen. No. 2,305,632) in dichloromethane, maintained below 0° C., is treated with two equivalents of sulphuryl chloride to give ethyl 2-(2,5-dichloro-1H-pyrrol-1-yl)propionate. Treatment of this ester with ammonia in the manner of Example 1, gives 2-(2,5-dichloro-1H-pyrrol-1-yl)propionamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04278685 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-64c5808e168d45d28f2230fc949eeee2 |
| Source note | uspto-grants-1981_07 |