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HRID12777

反应详情

EQUATION

反应方程式

HRID 12777 的结构方程式

REACTANTS

反应物

3
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：C1COCCO1
HCID31275

1,4-Dioxane

C4H8O2

结构：Cc1ncccc1-c1cn(CCCCN2C[C@@H]3C[C@]3(c3ccc(C(F)(F)F)cc3)C2)c(=O)[nH]c1=O
HCID24759341

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ncccc1-c1cn(CCCCN2C[C@@H]3C[C@]3(c3ccc(C(F)(F)F)cc3)C2)c(=O)[nH]c1=O.Cl.Cl
HCID68690825

未命名化合物

收率 36%

PROCEDURE

实验过程

5-(2-methyl-3-pyridinyl)-1-(4-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}butyl)-2,4(1H,3H)-pyrimidinedione was treated with 4N HCl in dioxane (2 eq), to give the title compound as a white powder. (68 mg, 36% yield)