2,2-Dimethoxyethylmethylamine → HCID 13020005, compound

Participants

Reaction Conditions

Reaction Steps

Ethyl[4-[3-(trifluoromethyl)phenoxy]-phenyl]carbamate (7.1 grams; 0.02 mol) and N-(2,2-dimethoxyethyl) methanamine (15 ml) were charged into a glass reaction vessel equipped with mechanical stirrer, thermometer and reflux condenser. The mixture was refluxed for about 36 hours at a temperature of about 120° C. The product was recrystallized from ethyl acetate, then recrystallized from hexane giving the desired product having a melting point of 86°-88° C.

Provenance & Evidence