Hydrochloric Acid → HCID 23451793, compound

HRID 1277842Notes

Reaction equation

HRID 1277842 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([CH:28]=[C:29]([C:31]#[N:32])[CH:30]=1)[O:6][C:7]1[C:12]([C:13]#[N:14])=[CH:11][C:10]([NH:15][C:16]([N:18]([CH2:20][CH:21](OC)OC)[CH3:19])=[O:17])=[CH:9][C:8]=1[C:26]#[N:27])#[N:2].Cl>O>[CH3:19][N:18]1[CH:20]=[CH:21][N:15]([C:10]2[CH:9]=[C:8]([C:26]#[N:27])[C:7]([O:6][C:5]3[CH:4]=[C:3]([C:1]#[N:2])[CH:30]=[C:29]([C:31]#[N:32])[CH:28]=3)=[C:12]([C:13]#[N:14])[CH:11]=2)[C:16]1=[O:17]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 23451764HCID 23451764, compound

Product 1

HCID 23451793HCID 23451793, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

N-[4-(3,5-Dicyanophenoxy)-3,5-dicyanophenyl]-N'-(2,2-dimethoxyethyl)-N'-methylurea (0.02 mole), water (30 ml) and concentrated hydrochloric acid (3 ml) are charged into a glass reaction vessel fitted with a mechanical stirrer, thermometer and condenser. The mixture is refluxed for a period of about 30 minutes then cooled and extracted with ethyl acetate. The extract is washed with dilute aqueous sodium bicarbonate, with two portion of water and is then dried. The ethyl acetate is removed by mild warming under reduced pressure to yield the desired product 1-methyl-3-[4-(3,5-dicyanophenoxy)3,5-dicyanophenyl]-4-imidazolin-2-one.

Workup

  1. customfitted with a mechanical stirrer
  2. temperatureThe mixture is refluxed for a period of about 30 minutes
  3. temperaturethen cooled
  4. extractionextracted with ethyl acetate
  5. washThe extract is washed with dilute aqueous sodium bicarbonate, with two portion of water
  6. customis then dried
  7. customThe ethyl acetate is removed
  8. temperatureby mild warming under reduced pressure

Sources & evidence

ORD record
ord-2662c1b7137f4e7baae1c4c8cb47aaf9
Source dataset
uspto-grants-1981_07
Patent number
US04279637

Reaction notes

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