反应详情

Solutions of 12.2 g hexylamine and 8.0 g o-iodobenzoyl chloride in a total of 20 ml tetrahydrofuran were reacted for 10 minutes. The tetrahydrofuran was removed by heating on a water bath at 65° for 10 minutes and 50 ml of water were added to precipitate the crude product. The precipitate was recovered as in Example 1 and recrystallized from a benzene/hexane mixture as white crystals, to yield 7.6 g of N-hexyl-o-iodobenzamide, m.p. 104°-105°, Rf 0.78.

1. customThe tetrahydrofuran was removed
2. temperatureby heating on a water bath at 65° for 10 minutes
3. addition50 ml of water were added
4. customto precipitate the crude product
5. customThe precipitate was recovered as in Example 1
6. customrecrystallized from a benzene/hexane mixture as white crystals