Hydrochloric Acid → HCID 12763965, compound

Participants

Reaction Steps

A mixture of 1 g of ethyl 5,8-dimethoxyimidazo-[1,2-a]-quinoline-2-carboxylate in a mixture of 10 ml of methanol and a 5% sodium carbonate solution was refluxed for 1 hour, and the resultant solution was acidified with dilute hydrochloric acid. The precipitate of 5,8-dimethoxyimidazo-[1,2-a]-quinoline-2-carboxylic acid thus formed was filtered off and was suspended in 10 ml of methanol. The mixture was acidified with HCl/methanol to obtain a clear solution from which the acid crystallized upon addition of diethyl ether to obtain the said acid melting at 248°-250° C.

Provenance & Evidence