Hydrochloric Acid → HCID 12763965, compound

HRID 1277959Notes

Reaction equation

HRID 1277959 reaction equation
[CH3:1][O:2][C:3]1[C:12]2[C:7](=[CH:8][C:9]([O:13][CH3:14])=[CH:10][CH:11]=2)[N:6]2[CH:15]=[C:16]([C:18]([O:20]CC)=[O:19])[N:17]=[C:5]2[CH:4]=1.C(=O)([O-])[O-].[Na+].[Na+].Cl>CO>[CH3:1][O:2][C:3]1[C:12]2[C:7](=[CH:8][C:9]([O:13][CH3:14])=[CH:10][CH:11]=2)[N:6]2[CH:15]=[C:16]([C:18]([OH:20])=[O:19])[N:17]=[C:5]2[CH:4]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 10340Sodium CarbonateHCID 12763966HCID 12763966, compound

Product 1

HCID 12763965HCID 12763965, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 1 g of ethyl 5,8-dimethoxyimidazo-[1,2-a]-quinoline-2-carboxylate in a mixture of 10 ml of methanol and a 5% sodium carbonate solution was refluxed for 1 hour, and the resultant solution was acidified with dilute hydrochloric acid. The precipitate of 5,8-dimethoxyimidazo-[1,2-a]-quinoline-2-carboxylic acid thus formed was filtered off and was suspended in 10 ml of methanol. The mixture was acidified with HCl/methanol to obtain a clear solution from which the acid crystallized upon addition of diethyl ether to obtain the said acid melting at 248°-250° C.

Sources & evidence

ORD record
ord-4f9f9141a0124cc9a7e320259edb71f5
Source dataset
uspto-grants-1981_07
Patent number
US04279912

Reaction notes

Loading…