反应详情

Boil 12.4 g of 2-(α-methoxycarbonyl-3,4-dimethoxybenzylidene)-1-methylpyrrolidine for 15 minutes with 40 ml of conc. hydrochloric acid. Cool the resulting reaction mixture before rendering it alkaline with sodium hydroxide solution. Filter off the thus-produced precipitate and recrystallize it from ethanol/water 2:1 to obtain 3.2 g (32% of theory) of title compound having a m.p. of 72°.

1. temperatureCool
2. customthe resulting reaction mixture
3. filtrationFilter off the thus-produced precipitate
4. customrecrystallize it from ethanol/water 2:1