反应详情

Dissolve 12.2 g of 3,4-dimethoxybenzylidene-1-methylpyrrolidine in methanol and reduce the pyrrolidine in the thus-obtained solution with Raney nickel/hydrogen. Filter off the catalyst and distil off the methanol before distilling the residue to obtain 9.6 g (79%) of the title compound with a b.p. of 90° at 0.005 mm of Hg. The m.p. of the picrate (from ethanol) is 105° to 106°.

1. filtrationFilter off the catalyst
2. customdistil off the methanol
3. distillationbefore distilling the residue