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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1278046Generated: October 25, 2026

HCID 13186905, compound → 4-[(1-Methylpyrrolidin-2-yl)methyl]aniline

https://huagongshe.com/reaction/1278046

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 13186905HCID 13186905—
CatalystHCID 178506448HCID 178506448—
SolventEthanolHCID 702—
Product4-[(1-Methylpyrrolidin-2-yl)methyl]anilineHCID 13186904—

Reaction Steps

Hydrogenate 18 g of 2-(4-nitrobenzyl)-1-methylpyrrolidine in ethanol with 300 mg of platinum dioxide/hydrogen. Filter the catalyst from the reaction mixture, concentrate the latter and recrystallize the thus-produced residue from n-hexane to obtain the title compound at a yield of 12.7 g (82% of theory).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04279918
Source datasetuspto-grants-1981_07
ORD IDord-1cb7867abf4a4a23b6ea281998cc6f6b
Source noteuspto-grants-1981_07