2-(4-Bromobenzylidene)-1-methylpyrrolidine → HCID 23452593, compound

HRID 1278048Notes

Reaction equation

HRID 1278048 reaction equation
[Br:1][C:2]1[CH:14]=[CH:13][C:5]([CH:6]=[C:7]2[CH2:11][CH2:10][CH2:9][N:8]2[CH3:12])=[CH:4][CH:3]=1>C(O)C.[Pt].[H][H]>[Br:1][C:2]1[CH:14]=[CH:13][C:5]([CH2:6][CH:7]2[CH2:11][CH2:10][CH2:9][N:8]2[CH3:12])=[CH:4][CH:3]=1

Participants

4

Reactant 1

HCID 538333142-(4-Bromobenzylidene)-1-methylpyrrolidine

Product 1

HCID 23452593HCID 23452593, compound

Reagents, catalysts & solvents 2

HCID 178506450HCID 178506450, compoundCatalystHCID 702EthanolSolvent

Procedure

Hydrogenate 21.5 g of 2-(4-bromobenzylidene)-1-methylpyrrolidine in 400 ml of ethanol with platinum on activated charcoal/hydrogen. Filter out the catalyst, concentrate the filtrate and distil the residue to obtain 18.5 g (85% of theory) of the title compound (b.p. 70° at 0.001 mm of Hg).

Workup

  1. filtrationFilter out the catalyst
  2. concentrationconcentrate the filtrate
  3. customdistil the residue

Sources & evidence

ORD record
ord-26f51f375edd4c238f0e1cedb920edf8
Source dataset
uspto-grants-1981_07
Patent number
US04279918

Reaction notes

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