反应详情

Add 3.72 g of methyl iodide dropwise, with stirring, to 5.5 g of 2-(4-chlorobenzyl)-1-methylpyrrolidine in 40 ml of acetone. Filter off the formed crystalline precipitate and recrystallize it twice from methanol/diethyl ether to obtain 6.9 g (75% of theory) of the title compound (m.p. 184° to 186°).

1. filtrationFilter off the formed crystalline precipitate
2. customrecrystallize it twice from methanol/diethyl ether