HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 2-(4-Chlorobenzyl)-1,1-dimethylpyrrolidinium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 2-[(4-Chlorophenyl)methyl]-1-methylpyrrolidine | HCID 23452505 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 2-(4-Chlorobenzyl)-1,1-dimethylpyrrolidinium iodide | HCID 23452584 | — |
Reaction Steps
Add 3.72 g of methyl iodide dropwise, with stirring, to 5.5 g of 2-(4-chlorobenzyl)-1-methylpyrrolidine in 40 ml of acetone. Filter off the formed crystalline precipitate and recrystallize it twice from methanol/diethyl ether to obtain 6.9 g (75% of theory) of the title compound (m.p. 184° to 186°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04279918 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-2a9000da7c0b47b48600caabb4867034 |
| Source note | uspto-grants-1981_07 |