Hydrazine → Veratrohydrazide

HRID 1278087Notes

Reaction equation

HRID 1278087 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[O:13][CH3:14])[C:6](OC)=[O:7].[NH2:15][NH2:16]>O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[O:13][CH3:14])[C:6]([NH:15][NH2:16])=[O:7]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 16522Methyl 3,4-Dimethoxybenzoate

Product 1

HCID 1530859Veratrohydrazide

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 9.8 g (0.05 mol) of methyl 3,4-dimethoxybenzoate and 15 ml of 85% water containing hydrazine was refluxed for 2.5 hours with stirring. The reaction mixture was cooled and the crystals formed were recovered by filtration and washed with water to provide 3,4-dimethoxybenzoic acid hydrazide. The yield was quantitative.

Workup

  1. temperaturewas refluxed for 2.5 hours
  2. temperatureThe reaction mixture was cooled
  3. customthe crystals formed
  4. filtrationwere recovered by filtration
  5. washwashed with water

Sources & evidence

ORD record
ord-347cd166ced1414490107c6db4607ad9
Source dataset
uspto-grants-1981_07
Patent number
US04279982

Reaction notes

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