Hydrochloric Acid → HCID 20221346, compound

HRID 1278172Notes

Reaction equation

HRID 1278172 reaction equation
Cl.[N+:2]([C:5]1[CH:13]=[CH:12][CH:11]=[CH:10][C:6]=1[CH2:7][CH2:8][Br:9])([O-])=O>>[NH2:2][C:5]1[CH:13]=[CH:12][CH:11]=[CH:10][C:6]=1[CH2:7][CH2:8][Br:9]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 123638782-Nitrophenethyl bromide

Product 1

HCID 20221346HCID 20221346, compound

Procedure

Stannous chloride and conc. hydrochloric acid are added to 2-nitrophenethyl bromide to obtain 2-aminophenethyl bromide and a cyclization of 2-aminophenethyl bromide is carried out to obtain the indolines (J. of the American Chemical Society Vol. 63, page 1563 (1941)).

Sources & evidence

ORD record
ord-bf89d25c6fa142ca9d03ab200c4c69e9
Source dataset
uspto-grants-1981_07
Patent number
US04280958

Reaction notes

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