HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-chloropyridine → Benzamide, 2-chloro-N-(((5-chloro-2-pyridinyl)amino)carbonyl)-6-fluoro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-chloropyridine | HCID 66174 | — |
| Reactant | 2-Chloro-6-fluorobenzoyl isocyanate | HCID 13051731 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | Benzamide, 2-chloro-N-(((5-chloro-2-pyridinyl)amino)carbonyl)-6-fluoro- | HCID 174171 | — |
Reaction Steps
An 0.4 g. portion of 5-chloro-2-aminopyridine was dissolved in 20 ml. of acetonitrile and reacted with 0.7 g. of 2-chloro-6-fluorobenzoyl isocyanate as described in Example 1. The yield was 0.65 g. of the product named above, m.p. 210°-215° C. Elemental analysis gave the following results:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281003 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-e22bda1ebe8941088433f53bb087c5a7 |
| Source note | uspto-grants-1981_07 |