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HRID1278178

反应详情

EQUATION

反应方程式

HRID 1278178 的结构方程式

REACTANTS

反应物

2
结构：Nc1ccc(Cl)cn1
HCID66174

2-Amino-5-chloropyridine

C5H5ClN2

结构：O=C=NC(=O)c1c(F)cccc1Cl
HCID13051731

2-Chloro-6-fluorobenzoyl isocyanate

C8H3ClFNO2

PRODUCTS

生成物

1
结构：O=C(NC(=O)c1c(F)cccc1Cl)Nc1ccc(Cl)cn1
HCID174171

Benzamide, 2-chloro-N-[[(5-chloro-2-pyridinyl)amino]carbonyl]-6-fluoro-

C13H8Cl2FN3O2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

An 0.4 g. portion of 5-chloro-2-aminopyridine was dissolved in 20 ml. of acetonitrile and reacted with 0.7 g. of 2-chloro-6-fluorobenzoyl isocyanate as described in Example 1. The yield was 0.65 g. of the product named above, m.p. 210°-215° C. Elemental analysis gave the following results:

WORKUP

后处理

  1. customElemental analysis gave the
  2. customfollowing results