HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-(trifluoromethyl)pyridine → 1-(2-Chloro-6-fluorobenzoyl)-3-(5-trifluoromethyl-2-pyridinyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-(trifluoromethyl)pyridine | HCID 735862 | — |
| Reactant | 2-Chloro-6-fluorobenzoyl isocyanate | HCID 13051731 | — |
| Product | 1-(2-Chloro-6-fluorobenzoyl)-3-(5-trifluoromethyl-2-pyridinyl)urea | HCID 20533138 | — |
Reaction Steps
A portion of 5-trifluoromethyl-2-aminopyridine is reacted with 2-chloro-6-fluorobenzoyl isocyanate as described in Example 1. The reaction mixture is evaporated under vacuum and the product is recrystallized to obtain the product named above.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281003 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-e5930e012c074200becefce690fb7738 |
| Source note | uspto-grants-1981_07 |