HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-fluorobenzamide → 1-(2-Chloro-6-fluorobenzoyl)-3-(5-bromo-2-pyridinyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-fluorobenzamide | HCID 98564 | — |
| Reactant | Phenyl (5-bromopyridin-2-yl)carbamate | HCID 63235910 | — |
| Product | 1-(2-Chloro-6-fluorobenzoyl)-3-(5-bromo-2-pyridinyl)urea | HCID 13023074 | — |
Reaction Steps
A portion of 2-chloro-6-fluorobenzamide is dissolved in an organic solvent, and 5-bromo-2-pyridinylaminocarboxylic acid, phenyl ester is added. The reaction mixture is stirred with heating for a period of time, and is then evaporated under vacuum. The product, identical to the product of Example 2 above, is isolated from the residue by recrystallization.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281003 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-46b19ca476ac4feb8cf12d4b47fcf43c |
| Source note | uspto-grants-1981_07 |