Dimethylformamide dimethyl acetal → HCID 2805911, compound

Participants

Reaction Steps

As for Example 1, 3-acetyl-6-methylpyridine is refluxed with N,N-dimethylformamide dimethylacetal to yield 3-dimethylamino-1-(6-methyl-3-pyridyl)-2-propen-1-one. The preceding compound is heated at reflux temperature for 6 hours with 3-amino-4-chloropyrazole in glacial acetic acid to give the product of the example.

Provenance & Evidence