Hydrogen Peroxide → HCID 70528953, compound

HRID 1278226Notes

Reaction equation

HRID 1278226 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:12]3[N:13]=[CH:14][C:15]([C:16]#[N:17])=[C:11]3[N:10]=[CH:9][CH:8]=2)[CH:2]=1.[OH:18]O>C(O)(=O)C>[N+:1]1([O-:18])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:12]3[N:13]=[CH:14][C:15]([C:16]#[N:17])=[C:11]3[N:10]=[CH:9][CH:8]=2)[CH:2]=1

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 112183037-(3-Pyridyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

Product 1

HCID 70528953HCID 70528953, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 4.42 g of 7-(3-pyridyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 50 ml. of glacial acetic acid and 5 ml. of 30% hydrogen peroxide is heated on a steam bath for 2 hours. The mixture is cooled, filtered and the solid recrystallized from acetic acid to give 2.05 g. of the product of the example, m.p. 294°-295° C.

Workup

  1. temperatureThe mixture is cooled
  2. filtrationfiltered
  3. customthe solid recrystallized from acetic acid
  4. customto give 2.05 g

Sources & evidence

ORD record
ord-2c3bc3ee61094ed28c2db2a902a5d311
Source dataset
uspto-grants-1981_07
Patent number
US04281000

Reaction notes

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