Hydrogen Peroxide → HCID 70568537, compound

HRID 1278227Notes

Reaction equation

HRID 1278227 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:12]3[N:13]=[CH:14][CH:15]=[C:11]3[N:10]=[CH:9][CH:8]=2)[CH:2]=1.[OH:16]O>C(O)(=O)C>[N+:1]1([O-:16])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:12]3[N:13]=[CH:14][CH:15]=[C:11]3[N:10]=[CH:9][CH:8]=2)[CH:2]=1

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 11206374HCID 11206374, compound

Product 1

HCID 70568537HCID 70568537, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 1.96 g. of 7-(3-pyridyl)pyrazolo[1,5-a]pyrimidine, 25 ml. of glacial acetic acid and 2 ml. of 30% hydrogen peroxide is heated on a steam bath for 2 hours. The solvent is removed and the residue crystallized from ethanol to give 0.85 g. of the product of the example, m.p. 223°-226° C.

Workup

  1. additionA mixture of 1.96 g
  2. customThe solvent is removed
  3. customthe residue crystallized from ethanol
  4. customto give 0.85 g

Sources & evidence

ORD record
ord-3b51be13445e4658a150853c13539f8c
Source dataset
uspto-grants-1981_07
Patent number
US04281000

Reaction notes

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