反应详情

A mixture of 25.0 g of 2-acetyl-6-methylpyridine and 35 ml. of N,N-dimethylformamide dimethylacetal is refluxed for 16 hours. The mixture is cooled and filtered to give 3-dimethylamino-1-(6-methyl-2-pyridyl)-2-propen-1-one as crystals, m.p. 97°-98° C.

1. temperatureThe mixture is cooled
2. filtrationfiltered