HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chlorobenzotriazole → 3-Chloro-7-(4-pyridyl)pyrazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chlorobenzotriazole | HCID 88761 | — |
| Reactant | 7-(Pyridin-4-yl)pyrazolo[1,5-a]pyrimidine | HCID 12766262 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Chloro-7-(4-pyridyl)pyrazolo[1,5-a]pyrimidine | HCID 12766266 | — |
Reaction Steps
To a mixture of 0.01 mole of 7-(4-pyridyl)pyrazolo[1,5-a]pyrimidine in cold dichloromethane is added 0.011 mole of N-chlorobenzotriazole. The mixture is stirred at room temperature for one hour and heated on a steam bath for 15 minutes. The product is worked up as for Example 62 to give the product of the example, m.p. 183°-184° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281000 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-e4b7236d8f354141876d6fa97b91a4e0 |
| Source note | uspto-grants-1981_07 |