Benzaldehyde → HCID 3054950, compound

HRID 1278276Notes

Reaction equation

HRID 1278276 reaction equation
[O:1]=[C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([CH2:11][C:12]([OH:14])=[O:13])[CH:9]=2)[CH2:4][CH2:3]1.[OH-].[K+].[CH:17](=O)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>CCO>[CH:17](=[C:3]1[C:2](=[O:1])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([CH2:11][C:12]([OH:14])=[O:13])[CH:9]=2)[CH2:4]1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

5

Reactant 3

HCID 240BenzaldehydeHCID 14797Potassium HydroxideHCID 30549485-Indanacetic acid, 3-oxo-

Product 1

HCID 3054950HCID 3054950, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3-Oxo-5-indaneacetic acid (4.94 g, 0.026 mol) was added to a stirred solution of 85% KOH (3.43 g, 0.052 mol) in EtOH (73 ml) containing benzaldehyde (2.76 g, 0.026 mol) at 10° C. and stirred for 40 minutes. The potassium salt of the precipitated product was filtered off, dissolved in H2O (100 ml) was acidified with conc. HCl to give the title product, m.p. 202°-4° C. (EtOH).

Workup

  1. filtrationThe potassium salt of the precipitated product was filtered off
  2. dissolutiondissolved in H2O (100 ml)

Sources & evidence

ORD record
ord-b7b0b7f6cd354d4fb3c7b51915217f6a
Source dataset
uspto-grants-1981_07
Patent number
US04281017

Reaction notes

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