Glycerol → HCID 70559363, compound

HRID 1278297Notes

Reaction equation

HRID 1278297 reaction equation
[CH2:1]([NH:15][C:16]1[CH:21]=[CH:20][C:19]([CH:22]([CH2:27][CH3:28])[C:23]([O:25][CH3:26])=[O:24])=[CH:18][CH:17]=1)[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].C1(C)C=CC(S(O)(=O)=O)=CC=1.[OH:40][CH2:41][CH:42](CO)[OH:43]>>[CH2:1]([NH:15][C:16]1[CH:21]=[CH:20][C:19]([CH:22]([CH2:27][CH3:28])[C:23]([O:25][CH2:26][CH:42]([OH:43])[CH2:41][OH:40])=[O:24])=[CH:18][CH:17]=1)[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Participants

4

Reactant 3

HCID 753GlycerolHCID 6101p-Toluenesulfonic acidHCID 70559161HCID 70559161, compound

Product 1

HCID 70559363HCID 70559363, compound

Procedure

A mixture of 2.25 g. of methyl 4-(4-tetradecenylamino)phenylbutyrate, 280 mg. of glycerol, and 1.37 g. of p-toluenesulfonic acid is heated at 180° C. for 18 hours and then is partitioned between ether and 3% aqueous sodium carbonate solution. The ether layer is separated, dried, and evaporated to yield the product as a white solid.

Workup

  1. additionA mixture of 2.25 g
  2. customis partitioned between ether and 3% aqueous sodium carbonate solution
  3. customThe ether layer is separated
  4. customdried
  5. customevaporated

Sources & evidence

ORD record
ord-f9f73c275c8c41caa7b53c38766a4b21
Source dataset
uspto-grants-1981_07
Patent number
US04281019

Reaction notes

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