Hydrogen Peroxide → HCID 21163807, compound

HRID 1278329Notes

Reaction equation

HRID 1278329 reaction equation
[CH2:1]([S:3][C:4]1[S:8][C:7]([C:9]([NH2:11])=[O:10])=[N:6][N:5]=1)[CH3:2].[OH:12]O>C(O)(=O)C>[CH2:1]([S:3]([C:4]1[S:8][C:7]([C:9]([NH2:11])=[O:10])=[N:6][N:5]=1)=[O:12])[CH3:2]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 21163802HCID 21163802, compound

Product 1

HCID 21163807HCID 21163807, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

38 g of 5-ethylthio-1,3,4-thiadiazole-2-carboxamide are dissolved at 40° C. in 400 ml of glacial acetic acid and are then slowly reacted with 22.6 ml of a 30% hydrogen peroxide upon stirring. The solution is kept for another 3 hours at the same temperature. At the end of this period the oxidation is sufficiently complete not to require any further addition of heat. After standing overnight the reaction mixture is stirred into two liters of icewater resulting in the precipitation of a solid material which is removed by suction and recrystallized from isopropanol.

Workup

  1. additionany further addition
  2. temperatureof heat
  3. waitAfter standing overnight
  4. stirringthe reaction mixture is stirred into two liters of icewater
  5. customresulting in the precipitation of a solid material which
  6. customis removed by suction
  7. customrecrystallized from isopropanol

Sources & evidence

ORD record
ord-4382fb9845f34b1e99c95a0ab3183193
Source dataset
uspto-grants-1981_07
Patent number
US04281121

Reaction notes

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