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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1278360Generated: October 31, 2026

Hydrochloric Acid → HCID 12881339, compound

https://huagongshe.com/reaction/1278360

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantAcrylic AcidHCID 6581—
ReactantHCID 12881325HCID 12881325—
SolventWaterHCID 962—
ProductHCID 12881339HCID 12881339—

Reaction Steps

A mixture of 8.35 g. of trans-3-(6-hydroxy-4-oxo-4H-quinazolin-3-yl)-2-propenoic acid methyl ester and 500 ml. of 6 N hydrochloric acid was stirred and refluxed for 15 minutes. After cooling, water was added and the resultant solid was filtered to yield 6.33 g., m.p. 294°-296°; of trans-3-hydroxy-4-oxo-4H-quinazolin-3-yl)-2-propenoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04281127
Source datasetuspto-grants-1981_07
ORD IDord-46c75d95f6da46739355cf68468ab4cb
Source noteuspto-grants-1981_07