HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycerol → 2,3-Dihydroxypropyl 4-(15-carbomethoxypentadecylamino)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycerol | HCID 753 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Methyl 4-(15-carbomethoxypentadecylamino)benzoate | HCID 12898274 | — |
| Product | 2,3-Dihydroxypropyl 4-(15-carbomethoxypentadecylamino)benzoate | HCID 21163245 | — |
Reaction Steps
A mixture of 2.25 g. of methyl 4-(15-carbomethoxypentadecylamino)benzoate, 280 mg. of glycerol, and 1.37 g. of p-toluenesulfonic acid is heated at 180° C. for 4 hours and then is partitioned between ether and 3% aqueous sodium carbonate solution. The ether layer is separated, dried, and evaporated to yield 2,3-dihydroxypropyl 4-(15-carbomethoxypentadecylamino)benzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281018 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-f29fec8ab7fc4a1f9cc6d6b4764dca12 |
| Source note | uspto-grants-1981_07 |