反应详情

A mixture of 2.25 g. of methyl 4-(15-carbomethoxypentadecylamino)benzoate, 280 mg. of glycerol, and 1.37 g. of p-toluenesulfonic acid is heated at 180° C. for 4 hours and then is partitioned between ether and 3% aqueous sodium carbonate solution. The ether layer is separated, dried, and evaporated to yield 2,3-dihydroxypropyl 4-(15-carbomethoxypentadecylamino)benzoate.

1. additionA mixture of 2.25 g
2. customis partitioned between ether and 3% aqueous sodium carbonate solution
3. customThe ether layer is separated
4. customdried
5. customevaporated