HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18430853, compound → HCID 18430868, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18430853 | HCID 18430853 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 18430868 | HCID 18430868 | — |
Reaction Steps
A mixture of 1-[[1-[2-(4-benzyl-1-piperazinyl)ethyl]cyclopentyl]methyl]-2-pyrrolidinone (408 mg) and palladium hydroxide (41 mg) in methanol (5.5 ml) was stirred under hydrogen (4 kg) for 7 hours. After hydrogen was replaced with nitrogen, the mixture was filtered through Celite. The filtrate was concentrated in vacuo to provide a yellow oil. (345 mg/100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06444677B2 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-c5747c3f7a514c8c8bae52d29e355774 |
| Source note | uspto-grants-2002_09 |