Allyl bromide → HCID 54187006, compound

HRID 127871Notes

Reaction equation

HRID 127871 reaction equation
[CH2:1]([O:3][P:4]([SH:8])[O:5][CH2:6][CH3:7])[CH3:2].CC[O-].[Na+].[CH2:13](Br)[CH:14]=[CH2:15]>C1C=CC=CC=1.C(O)C>[CH2:1]([O:3][P:4]([CH2:15][CH:14]=[CH2:13])(=[S:8])[O:5][CH2:6][CH3:7])[CH3:2]

Participants

6

Reactant 3

HCID 7841Allyl bromideHCID 2723922Sodium ethoxideHCID 11542817HCID 11542817, compound

Product 1

HCID 54187006HCID 54187006, compound

Reagents, catalysts & solvents 2

HCID 241BenzeneSolventHCID 702EthanolSolvent

Conditions

Temperature
40 °C

Procedure

1 mole of thiophosphorous acid O,O-diethyl ester was dissolved in 600 ml of absolute benzene, and 1 mole of sodium ethylate, dissolved in absolute ethanol, was added at 0°-5° C., while cooling. 1.15 moles of allyl bromide were added dropwise to this mixture at 0°-5° C. and the mixture was stirred at 10° to 20° C. for a further 2 hours and at 40° C. for 3 hours. The NaBr which had separated out was filtered off and the filtrate was distilled.

Workup

  1. additionwas added at 0°-5° C.
  2. temperaturewhile cooling
  3. customThe NaBr which had separated out
  4. filtrationwas filtered off
  5. distillationthe filtrate was distilled

Sources & evidence

ORD record
ord-faff3556ed08478f834a6c03004f1af5
Source dataset
uspto-grants-1981_03
Patent number
US04257987

Reaction notes

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