Hydrochloric Acid → HCID 178479554, compound

HRID 1278728Notes

Reaction equation

HRID 1278728 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]=[CH:7][C:8]#[N:9].[ClH:10].CC[OH:13]>>[ClH:10].[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]=[CH:7][C:8](=[NH:9])[OH:13]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 982312-Furanacrylonitrile, (E)-

Product 1

HCID 178479554HCID 178479554, compoundYield 63%

Procedure

A solution of 2-furanacrylonitrile (10.9 g; 91 mmol) in EtOH (75 mL) was cooled in an ice bath. The cold mixture was then saturated with hydrogen chloride. The reaction solution was refrigerated for 18 hours. The reaction mixture was concentrated to 20 mL and diethyl ether was added. The brown solid gave 10.5 g (63% yield) of 2-Furanacryloimidate hydrochloride which was used in the next reaction.

Workup

  1. concentrationThe reaction mixture was concentrated to 20 mL and diethyl ether
  2. additionwas added

Sources & evidence

ORD record
ord-aaa494a98cff435d93975d4401c4bf0b
Source dataset
uspto-grants-2002_09
Patent number
US06444694B1

Reaction notes

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