Diethanolamine → HCID 70116843, compound

HRID 1279139Notes

Reaction equation

HRID 1279139 reaction equation
[OH:1][N:2]1[C:7]([CH3:9])([CH3:8])[CH2:6][CH:5]([O:10][CH2:11][CH:12]2[O:14][CH2:13]2)[CH2:4][C:3]1([CH3:16])[CH3:15].[NH:17]([CH2:21][CH2:22][OH:23])[CH2:18][CH2:19][OH:20]>O>[OH:1][N:2]1[C:7]([CH3:9])([CH3:8])[CH2:6][CH:5]([O:10][CH2:11][CH:12]([OH:14])[CH2:13][N:17]([CH2:21][CH2:22][OH:23])[CH2:18][CH2:19][OH:20])[CH2:4][C:3]1([CH3:16])[CH3:15]

Participants

4

Reactant 2

HCID 8113DiethanolamineHCID 3662321HCID 3662321, compound

Product 1

HCID 70116843HCID 70116843, compoundYield 29.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 2.28 g (0.01 mol) of 1-oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine and 1.05 g (0.01 mol) of diethanolamine in 25 mL of water is stirred at ambient temperature for 16 hours. The solution is then extracted with methylene chloride. The methylene chloride extract is dried over anhydrous magnesium sulfate, filter and concentrated. The crude reaction product is purified by column chromatography to afford 1.0 g of the title compound as a red oil.

Workup

  1. extractionThe solution is then extracted with methylene chloride
  2. extractionThe methylene chloride extract
  3. dry with materialis dried over anhydrous magnesium sulfate
  4. filtrationfilter
  5. concentrationconcentrated
  6. customThe crude reaction product
  7. customis purified by column chromatography

Sources & evidence

ORD record
ord-c112b9e571024a568d6f4024d441f965
Source dataset
uspto-grants-2002_09
Patent number
US06447644B1

Reaction notes

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