HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 4-Methylisoquinolin-7-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 7-Methoxy-4-methylisoquinoline | HCID 20523203 | — |
| Product | 4-Methylisoquinolin-7-ol | HCID 20523221 | — |
Reaction Steps
A mixture of 17.3 g. (0.1 mole) of 7-methoxy-4-methylisoquinoline and 100 ml. of 48% hydrobromic acid is refluxed for sixteen hours and evaporated in vacuo. The residue is dissolved in water, neutralized with ammonium hydroxide and filtered to yield 7-hydroxy-4-methylisoquinoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04258049 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-948ffba10f3c482688859b302143d3f1 |
| Source note | uspto-grants-1981_03 |