HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminophenol → 5-p-Chlorophenyl-1-phenyl-4-(benzoxazol-2-ylmethyl)-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminophenol | HCID 5801 | — |
| Reactant | Pyrazole-4-acetic acid, 5-(p-chlorophenyl)-1-phenyl- | HCID 622583 | — |
| Product | 5-p-Chlorophenyl-1-phenyl-4-(benzoxazol-2-ylmethyl)-pyrazole | HCID 23470861 | — |
Reaction Steps
A mixture of 31.3 g of (5-p-chlorophenyl-1-phenyl-pyrazol-4-yl)-acetic acid, 10.9 g of o-aminophenol and 400 ml of polyphosphoric acid is heated at 175° for 2 hours. After cooling and the customary working up, 5-p-chlorophenyl-1-phenyl-4-(benzoxazol-2-ylmethyl)-pyrazole is obtained; m.p. 137°-139°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04258047 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-053e0840cb7740cf8b8fe79c0da37555 |
| Source note | uspto-grants-1981_03 |