Hydrochloric Acid → HCID 18770414, compound

HRID 1279475Notes

Reaction equation

HRID 1279475 reaction equation
[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6]([C:14]2[CH:59]=[CH:58][C:17]([C:18]([N:20]3[CH2:25][CH2:24][CH:23]([N:26]([CH3:57])[CH2:27][CH2:28][N:29]([CH:31]4[CH2:36][CH2:35][N:34]([C:37](=[O:56])[C:38]5[CH:43]=[CH:42][C:41]([C:44]6[CH:49]=[C:48]([O:50][CH3:51])[C:47]([O:52][CH3:53])=[C:46]([O:54][CH3:55])[CH:45]=6)=[CH:40][CH:39]=5)[CH2:33][CH2:32]4)[CH3:30])[CH2:22][CH2:21]3)=[O:19])=[CH:16][CH:15]=2)[CH:7]=[C:8]([O:12][CH3:13])[C:9]=1[O:10][CH3:11]>C(O)C>[ClH:1].[ClH:1].[CH3:55][O:54][C:46]1[CH:45]=[C:44]([C:41]2[CH:40]=[CH:39][C:38]([C:37]([N:34]3[CH2:33][CH2:32][CH:31]([N:29]([CH3:30])[CH2:28][CH2:27][N:26]([CH:23]4[CH2:22][CH2:21][N:20]([C:18](=[O:19])[C:17]5[CH:58]=[CH:59][C:14]([C:6]6[CH:7]=[C:8]([O:12][CH3:13])[C:9]([O:10][CH3:11])=[C:4]([O:3][CH3:2])[CH:5]=6)=[CH:15][CH:16]=5)[CH2:25][CH2:24]4)[CH3:57])[CH2:36][CH2:35]3)=[O:56])=[CH:43][CH:42]=2)[CH:49]=[C:48]([O:50][CH3:51])[C:47]=1[O:52][CH3:53]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 18770415HCID 18770415, compound

Product 1

HCID 18770414HCID 18770414, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Concentrated hydrochloric acid (0.030 ml; 0.36 mmol) was added to a solution of N,N′-bis[1-[4-(3,4,5-trimethoxyphenyl)benzoyl]-4-piperidinyl]-N,N′-dimethylethylenediamine (60 mg; 0.076 mmol) in ethanol (5 ml) and the reaction mixture was concentrated under reduced pressure. The concentrated residue was suspended in diethyl ether and collected by filtration to obtain the title compound as a colorless crystalline powder.

Workup

  1. concentrationthe reaction mixture was concentrated under reduced pressure
  2. filtrationcollected by filtration

Sources & evidence

ORD record
ord-948518d8de2842589e494341914e2ac4
Source dataset
uspto-grants-2002_09
Patent number
US06448242B1

Reaction notes

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