Ammonium Chloride → HCID 178425252, compound

HRID 1279509Notes

Reaction equation

HRID 1279509 reaction equation
CO[C:3]1[CH2:4][CH2:5][CH2:6][C:7]([CH3:11])([CH3:10])[CH2:8][N:9]=1.[Cl-:12].[NH4+:13]>CO>[ClH:12].[CH3:10][C:7]1([CH3:11])[CH2:8][NH:9][C:3](=[NH:13])[CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 18428605HCID 18428605, compound

Product 1

HCID 178425252HCID 178425252, compoundYield 91.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of EXAMPLE 63 (490 mg, 3.2 mmol) in 18 mL of MeOH was reacted with ammonium chloride (125 mg, 2.4 mmol) by the method of EXAMPLE 27 to yield 387 mg (69%) of the title material.

Sources & evidence

ORD record
ord-e16a8d69d77948c4a532ff1e6e89c2d5
Source dataset
uspto-grants-2002_09
Patent number
US06448286B1

Reaction notes

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