HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Isocyanate → 1-(1,1-Dimethylethyl)-3-methyl-1-(3,3,3-trichloro-2-hydroxypropyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | 3-(Tert-butylamino)-1,1,1-trichloropropan-2-ol | HCID 23471020 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 1-(1,1-Dimethylethyl)-3-methyl-1-(3,3,3-trichloro-2-hydroxypropyl)urea | HCID 23471018 | — |
| Product | 1-(1,1-Dimethylethyl)-3-methyl-1-[3,3,3-trichloro-2-(methylcarbamoyloxy)propyl]urea | HCID 23471019 | — |
Reaction Steps
The reaction of 3-(1,1-dimethylethylamino)-1,1,1-trichloro-2-propanol with methyl isocyanate normally takes place at -70° to +80° C. in an inert solvent such as chloroform to produce 1-(1,1-dimethylethyl)-3-methyl-1-(3,3,3-trichloro-2-hydroxypropyl)urea and 1-(1,1-dimethylethyl)-3-methyl-1-[3,3,3-trichloro-2-(methylcarbamoyloxy)propyl]urea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04258060 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-58cfff0211dc4dedbf7f1af58ace5c0d |
| Source note | uspto-grants-1981_03 |