HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Tetralone → 1,3,4,5-Tetrahydro-2H-1-benzazepin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Tetralone | HCID 10724 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1,3,4,5-Tetrahydro-2H-1-benzazepin-2-one | HCID 248580 | — |
Reaction Steps
A sample of alpha tetralone (Aldrich, 36.5 g, 0.25 mol) was converted to the title material by the method of EXAMPLE 50 using 19.5 g (0.3 mol) of sodium azide in a mixture of 300 mL of conc H2SO4 and 100 mL of CH2Cl2. This procedure yielded after recrystalization from EtOH 12.1 g (30%) of the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06448286B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-8f879f985b6b415ba260c1190b8abc66 |
| Source note | uspto-grants-2002_09 |