HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methyl-5-[3-[(tetrahydropyran-2-yl)oxy]propyl]pyrrolidin-2-one → 5-(3-Hydroxypropyl)-4-methylpyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methyl-5-[3-[(tetrahydropyran-2-yl)oxy]propyl]pyrrolidin-2-one | HCID 18428541 | — |
| Solvent | AcOH THF water | HCID 21877175 | — |
| Product | 5-(3-Hydroxypropyl)-4-methylpyrrolidin-2-one | HCID 18428563 | — |
Reaction Steps
A mixture of the title compound of EXAMPLE 234 is treated with acetic acid:THF:water (4:2:1), and concentrated. The resulting material is purified by column chromatography to yield the title material.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06448286B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-4650290ff8294fd889b38d8670fb4b5b |
| Source note | uspto-grants-2002_09 |