5-Chloro-2-nitrobenzoic acid → 5-Chloro-2-nitrobenzoyl chloride

HRID 1279602Notes

Reaction equation

HRID 1279602 reaction equation
[N+:1]([C:4]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][C:5]=1[C:6](O)=[O:7])([O-:3])=[O:2].S(Cl)([Cl:17])(=O)=O>>[N+:1]([C:4]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][C:5]=1[C:6]([Cl:17])=[O:7])([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 172865-Chloro-2-nitrobenzoic acidHCID 24648Sulfuryl chloride

Product 1

HCID 27236855-Chloro-2-nitrobenzoyl chloride

Procedure

A solution of 2-nitro-5-chlorobenzoic acid (200 mg) in sulfonylchloride (20 ml) was stirred for 4 hours at 99° C. in a stream of argon. After leaving to cool, the solution was concentrated under the reduced pressure to give the title compound.

Workup

  1. customAfter leaving
  2. temperatureto cool
  3. concentrationthe solution was concentrated under the reduced pressure

Sources & evidence

ORD record
ord-ecc8617ca8934d48b9f28cb879a0318f
Source dataset
uspto-grants-2002_09
Patent number
US06448290B1

Reaction notes

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