Glycine → N-Tritylglycine

HRID 1279752Notes

Reaction equation

HRID 1279752 reaction equation
[C:1](Cl)([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:21][CH2:22][C:23]([OH:25])=[O:24]>>[C:1]([NH:21][CH2:22][C:23]([OH:25])=[O:24])([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 750GlycineHCID 6456Trityl chloride

Product 1

HCID 248898N-TritylglycineYield 90%

Procedure

N-tritylglycine was prepared in 90% yield fro m trityl chloride and glycine according to the procedure of Zervas et al., J. Am. Chem. Soc. 78:1359 (1956).

Sources & evidence

ORD record
ord-26dd0f538e3e473fb2a77f199875ece1
Source dataset
uspto-grants-2002_09
Patent number
US06448412B1

Reaction notes

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